The H=xp model revisited and the Riemann zeros

Berry and Keating conjectured that the classical Hamiltonian H = xp is related to the Riemann zeros. A regularization of this model yields semiclassical energies that behave, in average, as the non trivial zeros of the Riemann zeta function. However, the classical trajectories are not closed, rendering the model incomplete. In this paper, we show that the Hamiltonian H = x (p + l_p^2/p) contains closed periodic orbits, and that its spectrum coincides with the average Riemann zeros. This result is generalized to Dirichlet L-functions using different self-adjoint extensions of H. We discuss the relation of our work to Polya's fake zeta function and suggest an experimental realization in terms of the Landau model.Comment: 5 pages, 3 figure

Online detection of pathological TCP flows with retransmissions in high-speed networks

Online Quality of Service (QoS) assessment in high speed networks is one of the key concerns for service providers, namely to detect QoS degradation on-the-fly as soon as possible and avoid customers’ complaints. In this regard, a Key Performance Indicator (KPI) is the number of TCP retransmissions per flow, which is related to packet losses or increased network and/or client/server latency. However, to accurately detect TCP retransmissions the whole sequence number list should be tracked which is a challenging task in multi-Gb/s networks. In this paper we show that the simplest approach of counting as a retransmission a packet whose sequence number is smaller than the previous one is enough to detect pathological flows with severe retransmissions. Such a lightweight approach eliminates the need of tracking the whole TCP flow history, which severely restricts traffic analysis throughput. Our findings show that low False Positive Rates (FPR) and False Negative Rates (FNR) can be achieved in the detection of such pathological flows with severe retransmissions, which are of paramount importance for QoS monitoring. Most importantly, we show that live detection of such pathological flows at 10 Gb/s rate per processing core is feasibleThis work has been partially funded by the Spanish Ministry of Economy and Competitiveness and the European Regional Development Fund under the projects TRÁFICA (MINECO/ FEDER TEC2015-69417-C2-1-R), Preproceso Inteligente de Tráfico (MINECO / FEDER TEC2015-69417-C2-2-R) and RACING DRONES (MINECO / FEDER RTC-2016-4744-7

On the design and performance evaluation of automatic traffic report generation systems with huge data volumes

In this paper, we analyze the performance issues involved in the generation of automated traffic reports for large IT infrastructures. Such reports allow the IT manager to proactively detect possible abnormal situations and roll out the corresponding corrective actions. With the ever‐increasing bandwidth of current networks, the design of automated traffic report generation systems is very challenging. In a first step, the huge volumes of collected traffic are transformed into enriched flow records obtained from diverse collectors and dissectors. Then, such flow records, along with time series obtained from the raw traffic, are further processed to produce a usable report. As will be shown, the data volume in flow records turns out to be very large as well and requires careful selection of the key performance indicators (KPIs) to be included in the report. In this regard, we discuss the use of high‐level languages versus low‐level approaches, in terms of speed and versatility. Furthermore, our design approach is targeted for rapid development in commodity hardware, which is essential to cost‐effectively tackle demanding traffic analysis scenarios. Actually, the paper shows feasibility of delivering a large number of KPIs, as will be detailed later, for several TBytes of traffic per day using a commodity hardware architecture and high‐level languagesThis work has been partially supported by the Spanish Ministry of Economy and Competitiveness and the European Regional Development Fund under the projects TRÁFICA (MINECO/FEDER TEC2015‐69417‐C2‐1‐R) and Procesado Inteligente de Tráfico (MINECO/FEDER TEC2015‐69417‐C2‐2‐

Cell therapy for spinal cord injury with Olfactory Ensheathing Glia Cells (OECs)

This is the peer reviewed version of the following article: Gómez RM, Sánchez MY, Portela-Lomba M, et al. Cell therapy for spinal cord injury with olfactoryensheathing glia cells (OECs). Glia. 2018;00:1–35 which has been published in final form at GLIA 13 January (2018) http://doi.org/10.1002/glia.23282. © 2018 Wiley Periodicals This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.The prospects of achieving regeneration in the central nervous system (CNS) have changed, asmost recent findings indicate that several species, including humans, can produce neurons in adult-hood. Studies targeting this property may be considered as potential therapeutic strategies torespond to injury or the effects of demyelinating diseases in the CNS. While CNS trauma mayinterrupt the axonal tracts that connect neurons with their targets, some neurons remain alive, asseen in optic nerve and spinal cord (SC) injuries (SCIs). The devastating consequences of SCIs aredue to the immediate and significant disruption of the ascending and descending spinal pathways,which result in varying degrees of motor and sensory impairment. Recent therapeutic studies forSCI have focused on cell transplantation in animal models, using cells capable of inducing axonregeneration like Schwann cells (SchCs), astrocytes, genetically modified fibroblasts and olfactoryensheathing glia cells (OECs). Nevertheless, and despite the improvements in such cell-based ther-apeutic strategies, there is still little information regarding the mechanisms underlying the successof transplantation and regarding any secondary effects. Therefore, further studies are needed to clarify these issues. In this review, we highlight the properties of OECs that make them suitable toachieve neuroplasticity/neuroregeneration in SCI. OECs can interact with the glial scar, stimulateangiogenesis, axon outgrowth and remyelination, improving functional outcomes following lesion.Furthermore, we present evidence of the utility of cell therapy with OECs to treat SCI, both fromanimal models and clinical studies performed on SCI patients, providing promising results for future treatments

DESARROLLO E IMPLEMENTACIÓN DE TECNOLOGÍAS BIOMÉDICAS PARA LA TELEREHABILITACIÓN FUNCIONAL

El presente artículo muestra el desarrollo e implementación de un sistema de telerehabilitación funcional empleando entornos virtuales interactivos y tecnologías biomédicas en pacientes con secuelas de parálisis cerebral con limitación en los movimientos de las extremidades superiores e inferiores. El sistema facilita la intervención terapéutica empleando la telerehabilitación a través de videojuegos con interfaz de adquisición de movimientos. La plataforma se desarrolló en un lenguaje de programación de fácil configuración, de tal forma que los terapeutas puedan cambiar y ajustar los retos de cada intervención terapéutica de forma interactiva, amigable y divertida, acorde al progreso y motivando al paciente a continuar con su evolución. Los resultados muestran mejora en niños con parálisis cerebral, con limitaciones en movimiento a nivel de miembros superiores o inferiores

[José Carrete] [Material gráfico]: [defensa]

Contiene fotografías pertenecientes al archivo fotográfico del diario "Región", publicadas entre 1971 y 1980Algunas fotos no indican autoría; el resto firmadas por Foto E. Gar (Oviedo), Foto Javier Blanco, Información Gráfica Sierra (Oviedo

Intestinal parasitism and nutritional status in preschool children in institutions at bogotá, dc

In order to assess the nutritional status of preschool children at institutions in the Capital District of Bogotá, 237 children aged between 24 and 76 months were studied. An anthropometric assessment was carried out together with measurement of blood parameters, hematocrit and hemoglobin concentration, and prevalence of intestinal parasites. The prevalence of Ascaris and pinworm was 0,5 % while Entamoeba histolytica was found in 3,5 % and Giardia in 14,9 %. Chronic and global malnutrition were found in 45,5 % and 38,8 %, respectively. The nutritional parameters in blood were within the normal ranges. Social and environmental variables did not present any significant changes. While basic hygienic habits were adequate, the level of knowledge on prevention was low. The possible meaning of these results is examined.Para evaluar la situación de niños preescolares en las instituciones del Distrito de Bogotá que prestan servicios a este tipo de población, se estudiaron 237 niños con edades entre 24 y 76 meses, con respecto a la prevalencia de parasitismos intestinales, la situación nutricional por medio de la evaluación del peso y la talla, la circunferencia del brazo, el espesor del pliegue del tríceps y de parámetros sanguíneos de hemoglobina y hematocrito. Ascaris y tricocéfalos se encontraron con una frecuencia del 0,5 % mientras que la Entamoeba histolytica se encontró en el 3,5 % y Giardia lamblia en el 14,9 %. Se encontraron desnutriciones crónica y global de 45,5 % y 38,8 % respectivamente. Los parámetros nutricionales en sangre estuvieron dentro de límites normales. Las variables sociales y ambientales no presentaron alteraciones de importancia. Mientras los hábitos básicos de higiene resultaron adecuados, el nivel de conocimiento sobre prevención fue precario. Se examina la posible significación de estos resultados

[Mario César Jacquet] [Material gráfico]: [defensa]

Contiene fotografías pertenecientes al archivo fotográfico del diario "Región", publicadas entre 1973 y 1980Algunas fotos no indican autoría; el resto firmadas por Foto E. Gar (Oviedo), Información Gráfica Sierra (Oviedo), Foto Javier Blanc

[Maxi] [Material gráfico]

Contiene fotografías pertenecientes al archivo fotográfico del diario "Región", publicadas entre 1975 y 1982Algunas fotos no indican autoría; el resto firmadas por Foto E. Gar (Oviedo), Foto Sierra (Oviedo), Foto Javier Blanc